Retrospective Analysis of Demographic, Epidemiologic, and Clinical Characteristics of Poisoning Cases Followed in Pediatric Intensive Care Unit
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    Research Article
    P: 72-78
    August 2019

    Retrospective Analysis of Demographic, Epidemiologic, and Clinical Characteristics of Poisoning Cases Followed in Pediatric Intensive Care Unit

    J Pediatr Emerg Intensive Care Med 2019;6(2):72-78
    1. Diyarbakır Çocuk Hastalıkları Hastanesi, Çocuk Yoğun Bakım Ünitesi, Diyarbakır, Türkiye
    2. Diyarbakır Çocuk Hastalıkları Hastanesi, Çocuk Acil Servisi Kliniği, Diyarbakır, Türkiye
    3. Diyarbakır Çocuk Hastalıkları Hastanesi, Çocuk Sağlığı ve Hastalıkları Kliniği, Diyarbakır, Türkiye
    No information available.
    No information available
    Received Date: 19.12.2018
    Accepted Date: 04.02.2019
    Publish Date: 17.06.2019
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    ABSTRACT

    Introduction:

    The aim of this study was to investigate demographic, epidemiologic, and clinical characteristics of cases admitted to pediatric intensive care unit (PICU) for poisoning.

    Methods:

    Cases with poisoning admitted to PICU between January 1, 2015 and June 30, 2016 were evaluated retrospectively.

    Results:

    Ninety two cases were enrolled in this study. The mean age was 63.65±59.1 months and 73.9% of the cases were under 5 years of age. Fifty five point four percent of the cases were male. Of the poisoning cases, 82.6% were accidental and 14.1% were suicidal. Seventy seven point two percent of the cases were drug related and 18.3% of them were multi-drug poisonings. Central nervous system drugs were the most frequently (24.2%) ingested drugs. The most common cause of non-drug poisonings were pesticide and insecticides (42.8%). The median duration of time from ingestion to admission to the pediatric emergency department was 60 (10-2880) minutes. Of the cases, 31.5% were symptomatic. Gastric lavage and activated charcoal were performed in 65.2% and 72.8% of the cases, respectively. Continuous venovenous hemodiafiltration was performed in 3 cases. The mean time of PICU and hospital stay were 19.53±14.37 and 35.91±29.46 hours, respectively. During the study period, one case died due to acute poisoning of alpha-lipoic acid.

    Conclusion:

    Pediatric poisonings are among the most common reasons for referrals to emergency department, admission to hospital and represent a preventable cause of morbidity and mortality. Parental education about prevention of poisoning and keeping drugs and household products out of children’s reach is important because most of the poisonings occur at home with drugs and household products. Recognition of epidemiologic and clinical characteristics of pediatric poisoning by healthcare providers is also important for rapid diagnosis and treatment.

    Keywords: Poisoning, pediatric intensive care unit, epidemiology, drug ingestion, suicide

    References

    1
    Nistor N1, Frasinariu OE1, Rugină A1, Ciomaga IM1, Jităreanu C2, Ştreangă V1. Epidemiological study on accidental poisonings in children from northeast Romania. Medicine (Baltimore). 2018;97:e11469.
    2
    Gummin DD, Mowry JB, Spyker DA, Brooks DE, Fraser MO, Banner W. 2016 annual report of the American Association of Poison Control Centers’ national poison data system (NPDS): 34th annual report. Clin Toxicol (Phila). 2017;55:1072-252.
    3
    Özcan N, İkincioğulları D. Ulusal zehir danışma merkezi 2008 yılı çalışma raporu özeti. Turk Hij Den Biyol Derg. 2009;66:ER:29-58.
    4
    Biçer S, Sezer S, Çetindağ F, Kesikminare M, Tombulca N, ve ark. Çocuk Acil Kliniği 2005 yılı akut zehirlenme olgularının değerlendirilmesi. Marmara Medical Journal. 2007;20:12-20.
    5
    Azab SM1, Hirshon Jm, Hayes Bd4, El-Setouhy M5,6, Smith Gs7, Sakr Ml1,8, Tawfik H8, Klein-Schwartz W9. Epidemiology of acute poisoning in children presenting to the poisoning treatment center at Ain Shams University in Cairo, Egypt, 2009-2013. Clin Toxicol (Phila). 2016;54:20-6.
    6
    Güngörer V1, Yisldırım NK1. Yeni Açılan İkinci Düzey Çocuk yoğun bakım birimimizde yatan zehirlenme olgularının değerlendirilmesi. Turk Pediatri Ars. 2016;51:35-9.
    7
    Tekerek NÜ, Dursun A, Akyıldız BN. Çocuk yoğun bakım ünitesinde takip edilen zehirlenme olgularının geriye dönük değerlendirilmesi. J Pediatr Emerg Intensive Care Med. 2016;3:21-6.
    8
    Yorulmaz A, Akbulut H, Yahya İ, Aktaş R, Emiroğlu HH, ve ark. Çocuk acil servisine zehirlenme nedeni ile başvuran olguların geriye dönük olarak değerlendirilmesi. J Pediatr Emerg Intensive Care Med. 2017;4:96-103.
    9
    Akgül F, Er A, Çelik FÇ, Çağlar A, Ulusoy E, ve ark. Çocukluk çağı zehirlenmelerinin geriye dönük olarak incelenmesi. J Pediatr Emerg Intensive Care Med. 2016;3:91-6.
    10
    Akin Y1, Ağzikuru T, Cömert S, Atilkan P, Erdağ GC, Telatar B. Hospitalizations for pediatric intoxication: a study from İstanbul. Turk J Pediatr. 2011;53:369-74.
    11
    Soyucen E, Aktan Y, Saral A, Akgün N, Numanoğlu AÜ. Sakarya bölgesinde çocukluk çağı zehirlenmelerinin geriye dönük değerlendirilmesi. Çocuk Sağlığı ve Hastalıkları Dergisi. 2006;49:301-6.
    12
    Kendirci HNP, Çolakoğlu EY, Hızlı Ş, Koçak M, Saylam E, ve ark. Hastanemiz çocuk acil servisine başvuran zehirlenme olgularının değerlendirilmesi. Türkiye Çocuk Hast Derg. 2011;5:29-35.
    13
    Andiran N1, Sarikayalar F. Pattern of acute poisonings in childhood in Ankara: what has changed in twenty years?. Turk J Pediatr. 2004;46:147-52.
    14
    Gauvin F1, Bailey B, Bratton SL. Hospitalizations for pediatric intoxication in Washington State, 1987-1997. Arch Pediatr Adolesc Med. 2001;155:1105-10.
    15
    Manzar N1, Saad SM, Manzar B, Fatima SS. The study of etiological and demographic characteristics of acute household accidental poisoning in children-a consecutive case series study from Pakistan. BMC Pediatr. 2010;3:10-28.
    16
    Lin YR1, Wu TK, Liu TA, Chou CC, Wu HP. Poison exposure and outcome of children admitted to a pediatric emergency department. World J Pediatr. 2011;7:143-9.
    17
    Biçer S, Yılmaz A, Keleş ES, Aydoğan G. Çocukluk çağı zehirlenmelerinde etiyolojik faktörlerin değerlendirilmesi. Turkiye Klinikleri J Pediatr. 2007;16:217-28.
    18
    Kizilyildiz BS1, Karaman K2, Özen S2, Üner A3. Acute intoxications among Turkish children. Minerva Pediatr. 2018;70:46-50.
    19
    Al Hazmi AM1. Patterns of accidental poisoning in children in Jeddah, Saudi Arabia. Ann Saudi Med. 1998;18:457-9.
    20
    Aji DY, İlter Ö. Türkiye’ de çocuk zehirlenmeleri. Türk Pediatri Ars. 1998;33:154-8.
    21
    Güzel IŞ, Kibar AE, Vidinlisan S. Çocuk acil servisine başvuran zehirlenme vakalarının demografik özelliklerinin incelenmesi. Genel Tıp Derg. 2011;21:101-7.
    22
    Even KM1, Armsby CC, Bateman ST. Poisonings requiring admission to the pediatric intensive care unit: a 5-year review. Clin Toxicol (Phila). 2014;52:519-24.
    23
    Kondolot M, Akyıldız B, Görözen F, Kurtoğlu S, Patıroğlu T. Çocuk acil servisine getirilen zehirlenme olgularının değerlendirilmesi. Çocuk Sağlığı ve Hastalıkları Dergisi. 2009;52:68-74.
    24
    Şevketoğlu E. Parasetamol Zehirlenmesi. İçinde: Çıtak A, Yılmaz HL (ed.ler). Pediatrik Zehirlenmeler. 1. Baskı. İstanbul, İstanbul Tıp Kitabevi, 2011:113-8.
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