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    E-ISSN: 2717-9206
    Outcomes of High-flow Nasal Cannula Oxygen Therapy on the Vital Signs of Children with Lower Respiratory Tract Diseases
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    Original Research
    VOLUME: 3 ISSUE: 3
    P: 121-130
    December 2016

    Outcomes of High-flow Nasal Cannula Oxygen Therapy on the Vital Signs of Children with Lower Respiratory Tract Diseases

    J Pediatr Emerg Intensive Care Med 2016;3(3):121-130
    DOI: 10.4274/cayd.38358
    Yakup Söğütlü 1
    Suat Biçer 2
    Gülçin Kurt 2
    Olcay Şah 2
    Medya Namdar 2
    Sevim Togaç 2
    Esen Besli 3
    Çiğdem Kaspar 4
    1. Marmara Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Pendik Eğitim ve Araştırma Hastanesi, Çocuk Acil Kliniği, İstanbul, Türkiye
    2. Marmara Üniversitesi Tip Fakültesi, Çocuk Sagligi Ve Hastaliklari Anabilim Dali, Pendik Egitim Ve Arastirma Hastanesi, Çocuk Acil Klinigi, Istanbul, Türkiye
    3. Yeditepe Üniversitesi Tip Fakültesi, Çocuk Sagligi Ve Hastaliklari Anabilim Dali, Istanbul, Türkiye
    4. Medeniyet Üniversitesi Tip Fakültesi, Göztepe Egitim Ve Arastirma Hastanesi, Çocuk Acil Klinigi, Istanbul, Türkiye
    5. Yeditepe Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, İstanbul, Türkiye
    6. Medeniyet Üniversitesi Tıp Fakültesi, Göztepe Eğitim ve Araştırma Hastanesi, Çocuk Acil Kliniği, İstanbul, Türkiye
    7. Yeditepe Üniversitesi Tıp Fakültesi, Biyoistatistik ve Tıbbi Bilişim Anabilim Dalı, İstanbul, Türkiye
    8. Yeditepe Üniversitesi Tip Fakültesi, Biyoistatistik Ve Tibbi Bilisim Anabilim Dali, Istanbul, Türkiye
    No information available.
    No information available
    Received Date: 21.10.2016
    Accepted Date: 20.11.2016
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    ABSTRACT

    Introduction:

    The aim of this study was to evaluate the effects of high-flow nasal cannula oxygen (HFNC) therapy on clinical findings and outcome before, during and after the implementation, by comparing changes in vital signs [respiratory rate (RR), heart rate, and arterial oxygen saturation (SpO2)] in children with lower respiratory tract disease.

    Methods:

    In this prospective observational study, clinical characteristics and outcomes of 32 children with bronchiolitis and pneumonia treated with HFNC in the pediatric emergency department were compared. Demographical and clinical features, changes in vital signs before and after treatment, and outcomes of all cases were determined and compared between two diagnostic groups.

    Results:

    The age of children with bronchiolitis (n=11) and pneumonia (n=21) treated by HFNC was between 1.5 and 204 months (mean: 24.59±38.46, median: 10 months). When compared with the baseline values, all vital sign measurements in mean decreased significantly from the 1st hour after the treatment (p<0.05). In all children, RR decreased significantly from the 1st hour after the treatment. The decline in mean RR continued till the 4th hour after treatment and reached the lowest level at the 8th hour. SpO2 values increased significantly at the 1st hour after treatment, and this increase continued in the next hours. The highest mean SpO2 was measured at the 24th hours after treatment. There was no significant difference in the mean values of vital signs between two diagnostic groups (p>0.05). Any probable adverse effects related with HFNC treatment were not observed.

    Conclusion:

    Since favorable outcomes observed in vital signs in children with lower respiratory tract diseases from the 1st hour after the treatment and no side effects related with HFNC treatment were observed, HFNC therapy can be considered an effective and reliable method.

    Keywords: Lower respiratory tract disease, bronchiolitis, child, pneumonia, outcome, vital sign, high-flow nasal cannula oxygen therapy

    References

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