A Case of Rhabdomyolysis Taking Senna
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    Case Report
    P: 160-163
    December 2019

    A Case of Rhabdomyolysis Taking Senna

    J Pediatr Emerg Intensive Care Med 2019;6(3):160-163
    1. Çukurova Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Acil Bilim Dalı, Adana, Türkiye
    2. Çukurova Üniversitesi Tıp Fakültesi, Çocuk Sağlığı ve Hastalıkları Anabilim Dalı, Çocuk Yoğun Bakım Bilim Dalı, Adana, Türkiye
    3. İstinye Üniversitesi Eczacılık Fakültesi, Farmasötik Botanik Anabilim Dalı, İstanbul, Türkiye
    No information available.
    No information available
    Received Date: 27.11.2017
    Accepted Date: 04.06.2018
    Publish Date: 21.10.2019
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    ABSTRACT

    Rhabdomyolysis (RML) is a clinical condition that results in the release of the cellular content into the circulation due to musculoskeletal damage caused by various causes. For this reason, emergency departments should recognize RML and start treatment without any delay. In this study, we present a case of secondary RML in a 14-year-old patient followed up with the diagnosis of subacute sclerosing panencephalitis. Respiratory and circulatory support was provided in the emergency unit and alkalization was started. All medications used by the patient were cut off. Hemodiafiltration treatment was performed in our intensive care unit. It was learned that the patient have used the senna plant regularly for five years because of constipation. It has been reported in the literature that the senna plant has toxic effects on the brain, liver, kidney, heart and muscle, and also may cause renal tubular necrosis, centrilobular hepatic necrosis and muscle fiber necrosis. In this case report, we aimed to emphasize that the senna plant sold by herbalists and used frequently by people may cause secondary RML which may be a life-threatening condition.

    Keywords: Rhabdomyolysis, senna, subakut sklerozan panensephalitis

    References

    1
    Vashishtha VM, John TJ, Kumar A. Clinical&Pathological features of acute toxicity due to cassia occidentalis in vertebrates. Indian Journal Medicine Res. 2009;130:23-30.
    2
    Sayın E. Piyasada aktarlarda satılan sinameki örnekleri üzerinde yapılan araştırmalar. Yüksek Lisans Tezi. Gazi Üniversitesi Sağlık Bilimleri Enstitüsü Ocak 2015.
    3
    Rabdomiyolizis. İçinde: Çocuk Acil Tıp: Kapsamlı ve Kolay Yaklaşım (Edt): Karaböcüoğlu M, Yılmaz HL, Duman M. Cilt II, Istanbul Tip Kitabevi, 2012;649.
    4
    Councelman FL. Rhabdomyolisis. In :Tintinalli JE, ed. Emergency Medicine a Comprehensive Study Guide. 5th ed. North Carolina: McGraw-Hill 2000;1841-4.
    5
    Yurteri G. Pilotlarda asemptomatik rabdomiyoliz. Türkiye Klinikleri J Case Rep. 2016;24:294-7.
    6
    Huang LY, Lin CM, Chiou CC, Lin WS, Cheng SM. Rhabdomyolysis as a potential complication of carbamazepine-induced toxic epidermal necrolysis. Clinical Biochemistry. 2012;45:153-1532.
    7
    Sarı O, Arslan E, Aydoğan Ü. Koç B. Halsizlık yorgunluk yakınması olmadan egzersiz sonrası gelişen bir rabdomyoliz olgusu. Euras J Fam Med. 2013;2:44-7.
    8
    European Pharmacopoeia. European Pharmacopoeia Commission. 2011;7:1236-8.
    9
    Demirezer Ö. Tedavide Kullanılan Bitkiler ‘’FFD Monografları’’. Nobel Tıp Kitabevleri 2007; 53-56.
    10
    Merz B, Werner C. Assessment report on cassia senna l. and cassia angustifolia, folium. European Medicines Agency Evaluation of Medicines for Human Use 2007; Doc. Ref. EMEA/HMPC/51868/2006 Corr: 32
    11
    Panwar RS, Kumar N. Cassia occidentalis toxicity causes recurrent out breaks of brain disease in children in Saharanpur. Indian Journal Medicine Res. 2008;127:413-4.
    12
    Rowe LD, Corrier DE, Reagor JC, Jones LP. Experimentally induced cassia emeriana poisoning in cattle and goats. American Journal of Veterinary Research. 1987;48:992-7.
    13
    Barbosa-Ferreira M, Daglı ML, Maiorka PC, Gorniak SL. Subacute in toxication by senna occidentalis seeds in rats. Food Chem Toxicol. 2005;43:497-503.
    14
    David CL. Effects of Casssiaobtusifolia (sicklepod) extract sandan thraquinones on musclemitochondrial function. Toxicon. 1989;27:519-29.
    15
    Huang LY, Lin CM, Chiou CC, Lin WS, Cheng SM. Rhabdomyolysis as a potential complication of carbamazepine-induced toxic epidermal necrolysis. Clinical Biochemistry. 2012;45:1531-2.
    16
    Jagannati M, Ramya I, Sathyendra S. Occupation-related chromium toxicity a rarecause of renal failture and rhabdomyolysis. Indian Journal of Enviromental Med. 2016:20:150-2.
    17
    Soyuncu S, Yıldıray C, Nokay AE. Portal vein thrombosis related to Cassia angustifolia. Clin Toxicol. 2008;46:774-7.
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