Öz
Koronavirüs hastalığı-2019 ilişkili çocuk multisistem enflamatuvar hastalık, şiddetli akut solunum sendromu-koronavirüs-2 enfeksiyonu geçiren çocuklarda ateş, karın ağrısı, hipotansiyon ve miyokardiyal işlev bozukluğuna yol açan şiddetli bir hastalık olarak tanımlanmıştır. Bununla birlikte bazı MIS-C olguları, yoğun bakım takibi gerektirecek çoğul organ yetmezliğine ilerlemektedirler. Şiddetli karın ağrısı, kusma ve yüksek ateş şikayeti olan, acil serviste akut apandisit tanısı konulan olguda izlemde MIS-C tanısı düşünülmüş ve akut apandisitin ender etiyolojik nedenlerinden paraziter enfestasyonu tespit edilmiştir. Bu olgu çoğul sistemik enflamatuvar sendromun (MIS-C) gastrointestinal sistem tutulumunun nadir bir bulgusu olan akut apandisit ile tanı alması ve akut apandisitin ender etiyolojik nedenlerinde paraziter enfestasyonu tespit edilmesi nedeniyle sunulmuştur.
Anahtar Kelimeler: MIS-C, COVID-19, akut apandisit, çocuk hasta
Kaynakça
World Health Organization (WHO). WHO Director-General’s opening remarks at the media briefing on COVID-19 - 11 March 2020. https://www.who.int/dg/speeches/detail/who Director-General’s opening remarks at the media briefing on COVID-19-11
Verdoni L, Mazza A, Gervasoni A, Martelli L, Ruggeri M, et al. An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study. Lancet. 2020;395:1771-8.
Viner RM, Whittaker E. Kawasaki-like disease: emerging complication during the COVID-19 pandemic. Lancet. 2020;395:1741-3.
Information for Healthcare Providers about Multisystem Inflammatory Syndrome in Children (MIS-C). Available online at: https://www.cdc.gov/mis/hcp/index.html
Pediatric Intensive Care Society. PICS Statement: Increased number of reported cases of novel presentation of multisystem inflammatory disease. https://picsociety.uk/ wpcontent/uploads/2020/04/PICS-statement-re-novel-KD-C19- presentation-v2-27042020.pdf
Yabanoğlu H, Aytaç HÖ, Türk E, Karagülle E, Calışkan K, et al. Parasitic infections of the appendix as a cause of appendectomy in adult patients. Turkiye Parazitol Derg. 2014;38:12-6.
Hoffmann J, Rasmussen OO. Aids in the diagnosis of acute appendicitis. Br J Surg. 1989;76:774-9.
Weisberg SP, Connors T, Zhu Y, Baldwin M, Lin W-H, et al. Antibody responses to SARS-CoV2 are distinct in children with MIS-C compared to adults with COVID-19. MedRxiv. 2020.
Çocuk Hasta Yönetimi ve Tedavi - Covid-19. https://covid19.saglik.gov.tr
Belhadjer Z, Méot M, Bajolle F, Khraiche D, Legendre A, et al. Acute Heart Failure in Multisystem Inflammatory Syndrome in Children in the Context of Global SARS-CoV-2 Pandemic. Circulation. 2020;142:429-36.
Altun E, Avci V, Azatcam M. Parasitic infestation in appendicitis. A retrospective analysis of 660 patients and brief literature review. Saudi Med J. 2017;38:314-8.
Henderson LA, Canna SW, Friedman KG, Gorelik M, Lapidus SK, et al. American College of Rheumatology Clinical Guidance for Multisystem Inflammatory Syndrome in Children Associated With SARS-CoV-2 and Hyperinflammation in Pediatric COVID-19: Version 1. Arthritis Rheumatol. 2020;72:1791-805.
Aslan N, Acari C, Çiçek T, Berk E. MIS-C Case Presented with Acute Appendicitis and Successfully Treated by Plasmapheresis. Turk Arch Pediatr. 2022;57:239-40.
Feldstein LR, Rose EB, Horwitz SM, Collins JP, Newhams MM, et al. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Engl J Med. 2020;383:334-46.
Yilmaz Ciftdogan D, Ekemen Keles Y, Karbuz A, Cetin BS, Elmas Bozdemir S, et al. Multisystem inflammatory syndrome in children associated with COVID-19 in 101 cases from Turkey (Turk-MISC study). J Paediatr Child Health. 2022;58:1069-78.
